The leaf of Costus pictus D. Don is considered as an antidiabetic in folklore medicine and is known to reduce the blood sugar, similar to insulin. PDF | To explore the micro morphology and physicochemical parameters of the leaves of Costus pictus D. Don (Costaceae). Macroscopy. Painted Spiral Ginger is a perennial herb, native to Mexico. It has long narrow leaves with a characteristic wavy edges. The bases of the sheaths are mottled with.

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In the present study, we found that body weight, food intake and water intake were significantly reduced in hypothyroid rats. Denirot F, Lang R. Pentacyclic triterpenes alpha and beta amyrins were identified and quantified in the extract. Effect of Vitamin E supplementation.

Further, the extract exhibited antioxidant and anti-inflammatory effects, improved plasma lipid profile and partially prevented hepatic and renal damage in hypothyroid rats. Then, biotin-conjugated FT3 was added to the microtiter plates. Amyrins could be responsible for the aforementioned beneficial effects exhibited by C. The glucose uptake was not enhanced by the extract of C. Differences between the groups were analyzed using one-way analysis of variance with Bonferroni post hoc test.

Int J Integr Biol. Despite this limitation, this model is still used worldwide till date because PTU-induced hypothyroid rat model mimics most of the main features of human hypothyroidism. Hypothyroidism is one of the most common endocrine diseases.


The data identified transcripts related to pathways of bixin, geranial and geraniol biosynthesis which are known to be peroxixome proliferator activated receptors PPAR agonists and anti-glycation agents.

Antidiabetic activity of methanol extract of Costus pictus D. Don, a non-model plant with potent anti-diabetic properties”. Effect of dietary wine pomace extract and oleanolic acid on plasma lipids in rats fed high-fat diet and its DNA microarray analysis.

The difference in mean values among the groups was analyzed using one-way analysis of variance ANOVA with Bonferroni post hoc picfus for anthropometric parameters, tissue oxidative stress markers and plasma inflammatory markers.

Biochemical and histological studies. This is the first study to reveal that C. Here, antibody specific to TSH was precoated onto microtiter plates. We found that C. Nat Prod Radiance ;3: Effect of the insulin plant Costus igneus leaves on dexamethasone-induced hyperglycemia.

Rats were then injected 2. costuw

Costus pictus – Painted Spiral Ginger

Ferric reducing antioxidant power; HDL: Aux gas flow rate was 15 Arb. J Indian Costu Clin Med ;2: Antihyperglycemic activity of Carulluma asttenuate. Plasma levels of free T3 and free T4 were significantly decreased and TSH levels were dramatically increased in hypothyroid group.

Management of type 2 diabetes: Table 2 Body weight, food intake and fluid intake of the experimental groups. Pentacyclic triterpenes alpha and beta amyrins were identified and quantified in the extract.


The present study was conducted to evaluate the effect of C. This was one of our quickest projects, which took us just five months to complete and publish. Medicinal plants of India with antidiabetic potential. Interactions between thyroid disorders and kidney disease.

This study therefore will aid in the understanding of the therapeutic potential of C.

It has been reported in previous studies that pentacyclic triterpenes such as betulinic pidtus alleviates experimental hypothyroidism. This model fails to produce increase in body weight as seen in human hypothyroidism.

Costus pictus ‘Red Stem’

The IC 50 value of positive control ascorbic acid was found to be 6. Hypothyroid group showed a profound elevation in both total cholesterol 1.


The increase in absorbance at nm was measured. We explored for the presence of pentacyclic triterpenes in C. Mechanism of impaired water excretion in the hypothyroid rat. Int J Curr Pharm Res. However, the possibility that the reason for the improvement in thyroid profile in C.